Need For Speed - Hot Pursuit 2 Key Generator ##VERIFIED##

Need For Speed - Hot Pursuit 2 Key Generator ##VERIFIED##

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In the previous issue of Therapeutic Advances in Gastroenterology we looked at the case of a young man with IBD who was successfully treated with a fecal microbiota transplant. Sibir et al. [[@bb0005]] describe the use of an arachnoid cyst, an extremely rare lesion, in order to deliver the fecal microbiota transplant. This is a highly unusual case report and it is important for us to keep this in context. For one, arachnoid cysts are benign lesions that grow slowly and do not cause clinical symptoms in the vast majority of patients who have them. Second, the patient described in the case study was successfully treated with a fecal microbiota transplant, which is not yet considered a first-line treatment for any condition. In fact, the consensus is that fecal microbiota transplants are not a valid treatment for any condition other than C. difficile infection. Third, the authors were not able to obtain a sample of the original fecal microbiota. Fourth, the authors did not report the use of any standardized bowel cleansing products, which is essential for obtaining a fecal microbiota sample. And finally, the authors did not report any follow up of the patient. So, while the case study is interesting, it is not really evidence-based and seems to be a bit of a piece of clinician-science. In fact, given the case study is not really evidence-based it is difficult to know exactly what the evidence is saying. Still, it is the case that fecal microbiota transplants can be used to treat IBD and that it can be performed without the need for bowel cleansing; so these are important observations. The case study also questions the value of using arachnoid cysts to deliver fecal microbiota transplants; and this is something that deserves more attention. So, this is an interesting case report, but it is not evidence-based and it raises some important questions that must be addressed. We can only hope that more data will be generated in the near future.

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